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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENAH
All Species:
7.27
Human Site:
S516
Identified Species:
16
UniProt:
Q8N8S7
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N8S7
NP_001008493.1
591
66510
S516
P
V
I
S
R
R
D
S
P
R
K
N
Q
I
V
Chimpanzee
Pan troglodytes
XP_001153142
726
79409
G517
S
E
I
H
L
S
D
G
Y
W
V
E
P
T
I
Rhesus Macaque
Macaca mulatta
XP_001104614
418
44787
T345
V
S
S
I
L
S
R
T
P
S
V
A
K
S
P
Dog
Lupus familis
XP_547511
806
87104
S731
P
V
I
S
R
R
D
S
P
R
K
N
Q
I
V
Cat
Felis silvestris
Mouse
Mus musculus
Q03173
802
85826
K727
S
T
P
E
P
T
R
K
P
W
E
R
T
N
T
Rat
Rattus norvegicus
O08719
393
42076
G320
P
P
N
S
S
E
A
G
R
K
P
W
E
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989631
784
84614
K709
S
T
P
E
L
T
R
K
P
W
E
R
T
N
T
Frog
Xenopus laevis
Q64GL0
692
73902
S558
T
D
A
N
R
T
S
S
G
G
G
G
G
G
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001014537
687
72309
G608
E
G
A
N
G
N
S
G
G
A
G
S
N
T
T
Honey Bee
Apis mellifera
XP_001122945
772
80833
S520
T
C
G
N
T
V
G
S
A
S
G
G
P
G
S
Nematode Worm
Caenorhab. elegans
P46504
980
115327
E888
S
T
N
S
I
K
S
E
I
D
L
S
H
I
H
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
30.5
40.9
64.3
N.A.
61.2
38.5
N.A.
N.A.
48.4
31
N.A.
N.A.
32.6
25.6
21.7
N.A.
Protein Similarity:
100
44.4
50
67.6
N.A.
64.5
48.9
N.A.
N.A.
55.8
44.9
N.A.
N.A.
47
42.3
33.7
N.A.
P-Site Identity:
100
13.3
6.6
100
N.A.
6.6
13.3
N.A.
N.A.
6.6
13.3
N.A.
N.A.
0
6.6
13.3
N.A.
P-Site Similarity:
100
20
20
100
N.A.
13.3
26.6
N.A.
N.A.
13.3
26.6
N.A.
N.A.
13.3
13.3
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
0
0
0
10
0
10
10
0
10
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
28
0
0
10
0
0
0
0
0
% D
% Glu:
10
10
0
19
0
10
0
10
0
0
19
10
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
10
0
10
0
10
28
19
10
28
19
10
19
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
10
% H
% Ile:
0
0
28
10
10
0
0
0
10
0
0
0
0
28
10
% I
% Lys:
0
0
0
0
0
10
0
19
0
10
19
0
10
0
0
% K
% Leu:
0
0
0
0
28
0
0
0
0
0
10
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
19
28
0
10
0
0
0
0
0
19
10
19
0
% N
% Pro:
28
10
19
0
10
0
0
0
46
0
10
0
19
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
19
0
0
% Q
% Arg:
0
0
0
0
28
19
28
0
10
19
0
19
0
10
0
% R
% Ser:
37
10
10
37
10
19
28
37
0
19
0
19
0
10
19
% S
% Thr:
19
28
0
0
10
28
0
10
0
0
0
0
19
19
28
% T
% Val:
10
19
0
0
0
10
0
0
0
0
19
0
0
0
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
28
0
10
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _